May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.1) Chu W.,et al.J. Biol. Chem. 270:10236-10245(1995).
Immunogen
This ANKRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-34 amino acids from human ANKRD1.
Ankyrin repeat domain-containing protein 1 Cardiac ankyrin repeat protein Cytokine-inducible gene C-193 protein Cytokine-inducible nuclear protein ANKRD1 C193 CARP HA1A2
Molecular Weight(MW)
36 kDa
Sequence Similarities
Predicted species reactivity based on immunogen sequence: Bovine
Western Blot at 1:2000 dilution + Caki-1 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:2000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.