Application
Western blot analysis of PRR5 in SK-N-SH cell lysate with PRR5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptideApplication
Immunohistochemistry of PPR5 in mouse brain tissue with PPR5 antibody at 5 ug/mL.Application
Immunofluorescence of PPR5 in mouse brain tissue with PPR5 antibody at 20 ug/mL.| Product Name | Protor 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Protor 1This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010] |
| Immunogen | PRR5 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human PRR5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| IF: 20 ug/mL: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | PRR5 PROTOR-1 proline rich 5 (renal) PROTOR1 PP610 FLJ20185k |
|---|---|
| Target | Protor 1 |
| Tissue Specificity | PRR5 antibody is predicted to not cross-react with other Protor protein family members. |
Application
Western blot analysis of PRR5 in SK-N-SH cell lysate with PRR5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide
Application
Immunohistochemistry of PPR5 in mouse brain tissue with PPR5 antibody at 5 ug/mL.
Application
Immunofluorescence of PPR5 in mouse brain tissue with PPR5 antibody at 20 ug/mL.| Application Notes | IF: 20 ug/mL: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
