ANXA8L2 is a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The protein may function as an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.1) Karanjawala, Z.E., (2008) Am. J. Surg. Pathol. 32 (2), 188-196.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ANXA8L2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
ANXA8L2 antibody can be used for detection of ANXA8L2 by ELISA at 1:1562500. ANXA8L2 antibody can be used for detection of ANXA8L2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Hum. Fetal Heart at 1 ug/ml.
Positive Control
1) Cat. No. 1211 - HepG2 Cell Lysate
Application Notes
ANXA8L2 antibody can be used for detection of ANXA8L2 by ELISA at 1:1562500. ANXA8L2 antibody can be used for detection of ANXA8L2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ANXA8L2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.