Application
Immunohistochemistry staining of APC2 in skin tissue using APC2 Antibody.| Product Name | APC2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APC2, Adenomatosis polyposis coli 2, APC-like, APCL |
| Product description | APC2, also known as Anaphase promoting complex subunit 2, APC2, Cyclosome subunit 2, and ANAPC2, is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains at least eleven subunits. The composition of APC is highly conserved in organisms from yeast to humans. APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10. |
| Immunogen | APC2 antibody was raised against amino acids 810 - 822 of APC2 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIPWB |
| APC2 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Sterile Filtration |
| Gene Symbol | APC2 |
|---|---|
| Alternative Names | APC2 Adenomatosis polyposis coli 2 APC-like APCL |
Application
Immunohistochemistry staining of APC2 in skin tissue using APC2 Antibody.| Application Notes | APC2 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store APC2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.01% sodium azide. |
