Aquaporin-1, AQP-1, Aquaporin-CHIP, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule, AQP1, CHIP28
Product description
Aquaporins are a family of small integral membrane
proteins related to the major intrinsic protein (MIP or AQP0). This
gene encodes an aquaporin which functions as a molecular water
channel protein. It is a homotetramer with 6 bilayer spanning
domains and N-glycosylation sites. The protein physically resembles
channel proteins and is abundant in erythrocytes and renal tubes.
The gene encoding this aquaporin is a possible candidate for
disorders involving imbalance in ocular fluid movement. Several
transcript variants encoding different isoforms have been found for
this gene.1) Chen, L.M., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299 (5), R1163-R1174 (2010) :
Immunogen
This AQP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human AQP1.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application
Western blot analysis in mouse brain tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.