Rho GTPases play a fundamental role in numerous cellular
processes that are initiated by extracellular stimuli that work
through G protein coupled receptors. The encoded protein may form
complex with G proteins and stimulate Rho-dependent signals. This
protein is similar to rat collybistin protein. Alternative splicing
of this gene generates two transcript variants which encode
different isoforms. Also there is possibility for the usage of
multiple polyadenylation sites for this gene.1) Lyons, R., et al. Leuk. Res. 34(1):109-115(2010)
Immunogen
This ARHGEF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-599 amino acids from the C-terminal region of human ARHGEF4.
Western blot analysis in human placenta tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.