Rho GTPases play a fundamental role in numerous cellular
processes initiated by extracellular stimuli that work through G
protein coupled receptors. The encoded protein may form a complex
with G proteins and stimulate Rho-dependent signals. This protein
may be involved in the control of cytoskeletal organization.1) Bailey, S.D., et al. Diabetes Care (2010) In press :
Immunogen
This ARHGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1503-1530 amino acids from the C-terminal region of human ARHGEF5.
Rho guanine nucleotide exchange factor 5 Ephexin-3 Guanine nucleotide regulatory protein TIM Oncogene TIM Transforming immortalized mammary oncogene p60 TIM ARHGEF5 TIM
Western blot analysis in A2058 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.