Application
Western blot analysis of ARSB in mouse lung tissue lysate with ARSB antibody at (A) 1 and (B) 2 μg/ml.Application
Immunofluorescence of ARSB in human lung tissue with ARSB antibody at 20 μg/mL.Application
Immunohistochemistry of ARSB in human lung tissue with ARSB antibody at 2.5 μg/mL.| Product Name | ARSB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARSB Antibody : ASB, G4S, MPS6, Arylsulfatase B, N-acetylgalactosamine-4-sulfatase, ASB |
| Product description | Aryl sulfatase B (ARSB) forms a homodimer that hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate (1). ARSB localizes to the lysozyme as well as to the extracellular matrix (2). Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B (3), and can be treated with exogenous ARSB (4).1) Wasserman SI and Austen KF. Arylsulfatase B of human lung. Isolation, characterization, and interaction with slow-reacting substance of anaphylaxis. J. Clin. Invest. 1976; 57:738-44. |
| Immunogen | ARSB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ARSB. The immunogen is located within amino acids 460 - 510 of ARSB . |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| ARSB antibody can be used for detection of ARSB by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ARSB |
|---|---|
| Alternative Names | ARSB Antibody : ASB G4S MPS6 Arylsulfatase B N-acetylgalactosamine-4-sulfatase ASB |
| Molecular Weight(MW) | Predicted: 59 kDa Observed: 57kDa |
| Sequence Similarities | 3) Cat. No. 10-101 - Human Lung Tissue Slide |
| Tissue Specificity | ARSB antibody is human, mouse and rat reactive. At least two isoforms of ARSB are known to exist; this antibody only recognizes the longest isoform. |
Application
Western blot analysis of ARSB in mouse lung tissue lysate with ARSB antibody at (A) 1 and (B) 2 μg/ml.
Application
Immunofluorescence of ARSB in human lung tissue with ARSB antibody at 20 μg/mL.
Application
Immunohistochemistry of ARSB in human lung tissue with ARSB antibody at 2.5 μg/mL.| Positive Control | 1) Cat. No. 1412 - Mouse Lung Tissue Lysate |
|---|---|
| Application Notes | ARSB antibody can be used for detection of ARSB by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ARSB antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | ARSB Antibody is supplied in PBS containing 0.02% sodium azide. |
