Ankyrin repeat and SOCS box protein 7, ASB-7, ASB7
Product description
The protein encoded by this gene belongs to a family of
ankyrin repeat proteins that, along with four other protein
families, contains a C-terminal SOCS box motif. Growing evidence
suggests that the SOCS box acts as a bridge between specific
substrate-binding domains and the more generic proteins that
comprise a large family of E3 ubiquitin protein ligases. In this
way, SOCS box containing proteins may regulate protein turnover by
targeting proteins for polyubiquination and, therefore, for
proteasome-mediated degradation. Two alternative transcripts
encoding different isoforms have been described. [provided by
RefSeq].1) Lamesch, P., et al. Genomics 89(3):307-315(2007)
Immunogen
This ASB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human ASB7.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.