ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.1) Yik, J.H., et al., (2002) J.Biol.Chem.277(43), 40844-40852.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASGR2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
ASGR2 antibody can be used for detection of ASGR2 by ELISA at 1:62500. ASGR2 antibody can be used for detection of ASGR2 by western blot at 4.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
ASGR2 antibody can be used for detection of ASGR2 by ELISA at 1:62500. ASGR2 antibody can be used for detection of ASGR2 by western blot at 4.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ASGR2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt