| Product Name | PSA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [ER-PR8] to PSAKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors. |
| Immunogen | Purified human prostate specific antigen. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | ER-PR8 |
| Host Species | Mouse |
| Tested Applications | IHC-PWB |
| For IHC-P: Use at a dilution of 1:100. For WB: Use at a dilution of 1:200. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | P07288 APS hK3 354 PSA 176820 KLK2A1 KLK3 |
|---|---|
| Target | PSA |
| Tissue Specificity | Reacts with the 33 kD human prostate specific antigen. |
| Cellular Localization | Cytoplasmic |
| Light Chain Type | kappa |
| Positive Control | LNCaP cells. Normal prostate or prostate carcinoma. |
|---|---|
| Application Notes | For IHC-P: Use at a dilution of 1:100. For WB: Use at a dilution of 1:200. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4 containing 0.2% BSA and 0.1% sodium azide |
