The protein encoded by this gene belongs to the family of
P-type cation transport ATPases, and to the subfamily of Na+/K+
-ATPases. Na+/K+ -ATPase is an integral membrane protein
responsible for establishing and maintaining the electrochemical
gradients of Na and K ions across the plasma membrane. These
gradients are essential for osmoregulation, for sodium-coupled
transport of a variety of organic and inorganic molecules, and for
electrical excitability of nerve and muscle. This enzyme is
composed of two subunits, a large catalytic subunit (alpha) and a
smaller glycoprotein subunit (beta). The catalytic subunit of
Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an
alpha 3 subunit.1) Einholm, A.P., et al. J. Biol. Chem. 285(34):26245-26254(2010)
Immunogen
This ATP1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-833 amino acids from the Central region of human ATP1A3.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.