ATP synthase subunit s, mitochondrial, ATP synthase-coupling factor B, FB, Mitochondrial ATP synthase regulatory component factor B, ATP5S, ATPW
Product description
This gene encodes a subunit of mitochondrial ATP synthase.
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an
electrochemical gradient of protons across the inner membrane
during oxidative phosphorylation. ATP synthase is composed of two
linked multi-subunit complexes: the soluble catalytic core, F1, and
the membrane-spanning component, Fo, comprising the proton channel.
This gene encodes the subunit s, also known as factor B, of the
proton channel. This subunit is necessary for the energy
transduction activity of the ATP synthase complexes. Alternatively
spliced transcript variants encoding different isoforms have been
identified.1) Ma, J., et al. Atherosclerosis 191(1):63-72(2007)
Immunogen
This ATP5S antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human ATP5S.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.