Application
Western blot analysis of PSD93 in rat brain membrane lysates using a 1:1000 dilution of| Product Name | PSD93 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [S18-30] to CHAPSYN-110 (PSD93) MAGUKRequired for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses. |
| Immunogen | Fusion protein amino acids 1-852 of rat Chapsyn-110; accession number Q63622 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | S18-30 |
| Host Species | Mouse |
| Tested Applications | IHCIPWB |
| We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | PSD93 Chapsyn-110 MGC131811 Chapsyn110 Chapsyn 110 |
|---|---|
| Target | CHAPSYN-110 (PSD93) MAGUK |
| Molecular Weight(MW) | 110kDa (note) |
| Tissue Specificity | No cross-reactivity against other MAGUK family members, PSD95, SAP97, SAP102, expressed in transfected cells. |
| Cellular Localization | Concentrated in soma and postsynaptic density of a subset of neurons. |
Application
Western blot analysis of PSD93 in rat brain membrane lysates using a 1:1000 dilution of| Application Notes | We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS pH7.4, 50% glycerol |
