Application
Immunohistochemistry staining of B2M in kidney tissue using B2M monoclonal Antibody.| Product Name | B2M Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | B2M, Beta 2 Microglobulin, Beta-2-microglobulin, Beta-2-microglobin |
| Product description | beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes. Beta 2-microglobulin is the low molecular weight component of HLA antigens and as such is involved in the presentation of endogenous antigens, activation of T lymphocytes and functional emergence of natural killer cells. It is found in the serum of normal individuals and in the urine in elevated amounts in patients with Wilson disease, cadmium poisoning and other conditions leading renal tubular dysfunction. ESTs have been isolated from libraries generated using virtually every tissue in the body. |
| Immunogen | B2M monoclonal antibody was raised against purified B2M (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | ELISAFACSIHCIPRIAWB |
| ELISA, FACS (1 ug/ml), ICC, IHC-P (10 ug/ml), Inhb, IP, RIA, WB (2 - 4 ug/ml): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | B2M |
|---|---|
| Alternative Names | B2M Beta 2 Microglobulin Beta-2-microglobulin Beta-2-microglobin |
| Tissue Specificity | Reacts with beta2-microglobulin (beta2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin. |
Application
Immunohistochemistry staining of B2M in kidney tissue using B2M monoclonal Antibody.| Application Notes | ELISA, FACS (1 ug/ml), ICC, IHC-P (10 ug/ml), Inhb, IP, RIA, WB (2 - 4 ug/ml): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | B2M antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 15 mM sodium azide, approx., pH 7.4. |
