Application
Western blot analysis of B4GALT2 Antibody in mouse testis tissue lysates (35ug/lane)| Product Name | B4GALT2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | B4GALT2 is one of type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue.1) Brockhausen, I., et al. Biochim. Biophys. Acta 1790(10):1244-1257(2009) |
| Immunogen | This B4GALT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the C-terminal region of human B4GALT2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | B4GALT2 |
|---|---|
| Alternative Names | Beta-1 4-galactosyltransferase 2 Beta-1 4-GalTase 2 Beta4Gal-T2 b4Gal-T2 241- UDP-Gal:beta-GlcNAc beta-1 4-galactosyltransferase 2 UDP-galactose:beta-N-acetylglucosamine beta-1 4-galactosyltransferase 2 Lactose synthase A protein N-acetyllactosamin |
| Molecular Weight(MW) | 42 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Hamster |
Application
Western blot analysis of B4GALT2 Antibody in mouse testis tissue lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
