Application
Various tissue extracts (50 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PSD95 antibody diluted at 1:5000.| Product Name | PSD95 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PSD95 (discs, large homolog 4 (Drosophila))Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human PSD95. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | MouseRat |
| Predicted Reactivity | Human, Rhesus Monkey, BovineHuman (100%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Dlg4 antibody , Dlgh4 antibody , SAP90 antibody , SAP90A antibody , discs, large homolog 4 (Drosophila) antibody |
|---|---|
| Target | PSD95 |
| Molecular Weight(MW) | 80 kDa (note) (2) |
| Cellular Localization | Membrane , Cell junction , synapse , postsynaptic cell membrane , postsynaptic density , synapse |
Application
Various tissue extracts (50 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PSD95 antibody diluted at 1:5000.| Positive Control | mouse brain , rat brain |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
