Application
Immunohistochemistry staining of BACE1 in pancreas tissue using BACE1 Antibody.| Product Name | BACE1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. |
| Immunogen | BACE1 antibody was raised against a peptide located near the internal domain of BACE1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| BACE1 antibody can be used in immunohistochemistry starting at 1:50. | |
| Species Reactivity | BatBovineDogGibbonGuinea PigHamsterHorseHumanMonkeyMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BACE1 |
|---|---|
| Alternative Names | BACE1 APP beta-secretase Asp 2 ASP2 Aspartyl protease 2 Aspartylprotease 2 Beta-secretase Beta-site APP-cleaving enzyme BACE HSPC104 KIAA1149 B-Secretase Beta-secretase 1 Memapsin-2 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of BACE1 in pancreas tissue using BACE1 Antibody.| Application Notes | BACE1 antibody can be used in immunohistochemistry starting at 1:50. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | BACE1 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
