BACH1 (also known as BRCA1 interacting protein C-terminal helicase 1, BRCA1-interacting protein 1 and BRCA1-associated C-terminal helicase 1) is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). The BACH1 gene may be a target of germline cancer-inducing mutations. BACH1 is localized within the nucleus and functions as a DNA-dependent ATPase and 5' to 3' DNA helicase. Two isoforms have been identified for this protein.
Immunogen
BACH1 antibody was raised against amino acids 92-104 of BACH1 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIFIHCWB
BACH1 antibody can be used in ELISA starting at 1:10000 - 1:50000, Western Blot starting at 1:1000 - 1:2500, and immunohistochemistry starting at 5 μg/mL.
Immunohistochemistry staining of BACH1 in skeletal muscle tissue using BACH1 Antibody.
Application Notes
BACH1 antibody can be used in ELISA starting at 1:10000 - 1:50000, Western Blot starting at 1:1000 - 1:2500, and immunohistochemistry starting at 5 μg/mL.
Additional Information
Form
Liquid
Storage Instructions
Store BACH1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.