This gene encodes a transcription factor that belongs to
the cap'n'collar type of basic region leucine zipper factor family
(CNC-bZip). The encoded protein contains broad complex, tramtrack,
bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is
atypical of CNC-bZip family members. These BTB/POZ domains
facilitate protein-protein interactions and formation of homo-
and/or hetero-oligomers. When this encoded protein forms a
heterodimer with MafK, it functions as a repressor of Maf
recognition element (MARE) and transcription is repressed. Multiple
alternatively spliced transcript variants have been identified for
this gene.1) Miyazaki, T., et al. Cancer Sci. 101(6):1409-1416(2010)
Immunogen
This BACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 670-698 amino acids from the C-terminal region of human BACH1.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.