Application
Immunohistochemistry of BAFF-R in human spleen tissue with BAFF-R antibody at 5 μg/mL.Application
Immunohistochemistry of BAFF Receptor in human tonsil tissue with BAFF Receptor antibody at 5 μg/mL.Application
Immunofluorescence of BAFF-R in human spleen tissue with BAFF-R antibody at 20 μg/ml.Application
Western blot analysis of BAFF Receptor in human (H), mouse (M), and rat (R) spleen tissue lysates with BAFF Receptor antibody at 5 μg/mL.| Product Name | BAFF Receptor Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | BAFF Receptor Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-κB and c-jun N-terminal kinase.1) Moore PA, Belvedere O, Orr A, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999;285:260-3 |
| Immunogen | BAFF Receptor antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of human BAFF Receptor The peptide sequence is identical between human and mouse origin. The immunogen is located within the last 50 ami |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| BAFF Receptor antibody can be used for detection of BAFF Rexeptor by Western blot at 5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNFRSF13C |
|---|---|
| Alternative Names | BAFF Receptor Antibody: BAFFR CD268 CVID4 BAFF-R BROMIX prolixin BAFFR BR3 Tumor necrosis factor receptor superfamily member 13C B-cell-activating factor receptor |
| Molecular Weight(MW) | 20 kDa |
| Sequence Similarities | 4) Cat. No. 1315 - Human Tonsil Tissue Lysate |
Application
Immunohistochemistry of BAFF-R in human spleen tissue with BAFF-R antibody at 5 μg/mL.
Application
Immunohistochemistry of BAFF Receptor in human tonsil tissue with BAFF Receptor antibody at 5 μg/mL.
Application
Immunofluorescence of BAFF-R in human spleen tissue with BAFF-R antibody at 20 μg/ml.
Application
Western blot analysis of BAFF Receptor in human (H), mouse (M), and rat (R) spleen tissue lysates with BAFF Receptor antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 1306 - Human Spleen Tissue Lysate |
|---|---|
| Application Notes | BAFF Receptor antibody can be used for detection of BAFF Rexeptor by Western blot at 5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | BAFF Receptor antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | BAFF Receptor Antibody is supplied in PBS containing 0.02% sodium azide. |
