Application
Immunohistochemistry staining of TNFRSF13C in tonsil tissue using TNFRSF13C monoclonal Antibody.| Product Name | TNFRSF13C Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFRSF13C, BAFFR, BR3, BAFF receptor, BLyS receptor 3, CD268, CD268 antigen, CVID4, Prolixin, BAFF-R, BROMIX |
| Product description | Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kappaB and c-jun N-terminal kinase. |
| Immunogen | TNFRSF13C monoclonal antibody was raised against BAFF - R - L1.2 transfectants of TNFRSF13C (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | FACSIHC |
| TNFRSF13C antibody can be used in Western Blot, and immunohistochemistry starting at 1:50.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNFRSF13C |
|---|---|
| Alternative Names | TNFRSF13C BAFFR BR3 BAFF receptor BLyS receptor 3 CD268 CD268 antigen CVID4 Prolixin BAFF-R BROMIX |
Application
Immunohistochemistry staining of TNFRSF13C in tonsil tissue using TNFRSF13C monoclonal Antibody.| Application Notes | TNFRSF13C antibody can be used in Western Blot, and immunohistochemistry starting at 1:50.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store TNFRSF13C antibody at 4 ˚C. Do not freeze. |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide. |
