BAG5 is a member of the
BAG1-related protein family. BAG1 is an anti-apoptotic protein that
functions through interactions with a variety of cell apoptosis and
growth related proteins including BCL-2, Raf-protein kinase,
steroid hormone receptors, growth factor receptors and members of
the heat shock protein 70 kDa family. This protein contains a BAG
domain near the C-terminus, which could bind and inhibit the
chaperone activity of Hsc70/Hsp70. Three transcript variants
encoding two different isoforms have been found for this gene.1) Bailey, S.D., et al. Diabetes Care (2010) In press :
Immunogen
This BAG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human BAG5.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.