This gene was first characterized as part of a cluster of
genes located within the human major histocompatibility complex
class III region. This gene encodes a nuclear protein that is
cleaved by caspase 3 and is implicated in the control of apoptosis.
In addition, the protein forms a complex with E1A binding protein
p300 and is required for the acetylation of p53 in response to DNA
damage. Multiple transcript variants encoding different isoforms
have been found for this gene.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This BAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1072-1099 amino acids from the C-terminal region of human BAT3.
Large proline-rich protein BAG6 BAG family molecular chaperone regulator 6 BCL2-associated athanogene 6 BAG-6 BAG6 HLA-B-associated transcript 3 Protein G3 Protein Scythe BAG6 BAT3 G3
Molecular Weight(MW)
119 kDa
Sequence Similarities
Predicted species reactivity based on immunogen sequence: Mouse
Western blot analysis in A2058 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.