Application
Antibody used in IHC on Human Spleen at 5.0 ug/ml.Application
Antibody used in WB on Human heart at 0.2-1 ug/ml.| Product Name | BCL11A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | BCL11A Is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.1) Uda, M., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (5), 1620-1625. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCL11A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| BCL11A antibody can be used for detection of BCL11A by ELISA at 1:1562500. BCL11A antibody can be used for detection of BCL11A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BCL11A |
|---|---|
| Alternative Names | BCL11A BCL11A-L BCL11A-S BCL11A-XL CTIP1 EVI9 FLJ10173 FLJ34997 HBFQTL5 KIAA1809 ZNF856 BCL11a-M |
| Molecular Weight(MW) | 91 kDa |
Application
Antibody used in IHC on Human Spleen at 5.0 ug/ml.
Application
Antibody used in WB on Human heart at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10407 - Fetal Heart Tissue Lysate |
|---|---|
| Application Notes | BCL11A antibody can be used for detection of BCL11A by ELISA at 1:1562500. BCL11A antibody can be used for detection of BCL11A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store BCL11A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
