Application
Western blot analysis of BCL3 in 293 cell lysate with BCL3 antibody at 1 μg/mL.| Product Name | BCL3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | BCL3 Antibody: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-κ-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-κ-B proteins. The expression of this gene can be induced by NF-κ-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-κ-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.1) Ohno H, Takimoto G, and McKeithan TW. The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control. Cell 1990; 60:991-7. |
| Immunogen | Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3. The immunogen is located within amino acids 360 - 410 of BCL3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BCL3 |
|---|---|
| Alternative Names | BCL3 Antibody: BCL4 D19S37 BCL4 B-cell lymphoma 3 protein Proto-oncogene BCL3 BCL-3 |
| Molecular Weight(MW) | Predicted: 50 kDa |
Application
Western blot analysis of BCL3 in 293 cell lysate with BCL3 antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 1210 - 293 Cell Lysate |
|---|---|
| Application Notes | BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | BCL3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | BCL3 Antibody is supplied in PBS containing 0.02% sodium azide. |
