The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.
Immunogen
Amino acids 1319 to 1335 of human BLM
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC
BLM antibody can be used in ELISA starting at 1:5000 - 1:20000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation:
Immunohistochemistry staining of BLM in thymus tissue using BLM Antibody.
Application Notes
BLM antibody can be used in ELISA starting at 1:5000 - 1:20000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation:
Additional Information
Form
Liquid
Storage Instructions
BLM antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.