| Product Name | Anti-Phospho-Blooms Syndrome Protein Blm (Thr99) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Thr99 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BLM |
|---|---|
| Gene Synonyms | BS RECQ2 RECQL2 RECQL3 MGRISCE1 |
| Gene Full Name | BLM RecQ like helicase |
| Gene Summary | The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. [provided by RefSeq, May 2020] |
| Alternative Names | Blm BLM_HUMAN Bloom syndrome Bloom syndrome protein Bloom syndrome RecQ helicase like BS DNA helicase DNA helicase RecQ like type 2 MGC126616 MGC131618 MGC131620 RECQ 2 RECQ like RecQ like type 2 RecQ protein like 3 RecQ protein-like 3 RecQ-like type 2 RecQ2 RECQL 2 RECQL 3 RECQL2 RECQL3 type 2 |
| Molecular Weight(MW) | 159 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P54132 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
