Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1, BRD7, BP75, CELTIX1
Product description
This gene encodes a protein which is a member of the
bromodomain-containing protein family. The product of this gene has
been identified as a component of one form of the SWI/SNF chromatin
remodeling complex, and as a protein which interacts with p53 and
is required for p53-dependent oncogene-induced senescence which
prevents tumor growth. Pseudogenes have been described on
chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in
multiple transcript variants.1) Burrows, A.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14280-14285(2010)
Immunogen
This BRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human BRD7.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.