This gene encodes one of the three subunits of the RNA
polymerase III transcription factor complex. This complex plays a
central role in transcription initiation by RNA polymerase III on
genes encoding tRNA, 5S rRNA, and other small structural RNAs. The
gene product belongs to the TF2B family. Two alternatively spliced
variants encoding different isoforms, that function at different
promoters transcribed by RNA polymerase III, have been identified.
Other transcript variants are possible, but their full-length
natures have not been completely characterized. [provided by
RefSeq].1) Haurie, V., et al. Proc. Natl. Acad. Sci. U.S.A. 107(9):4176-4181(2010)
Immunogen
This BRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the Central region of human BRF1.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.