Application
Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 μg/mL.Application
Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 μg/mL.Application
Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 μg/ml.| Product Name | BTLA Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BTLA Antibody : BTLA1, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein |
| Product description | The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).1) Carreno BM and Collins M. BTLA: a new inhibitory receptor with a B7-like ligand. Trends Immunol. 2003; 24:524-7. |
| Immunogen | BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA. The immunogen is located within amino acids 170 - 220 of BTLA . |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| BTLA antibody can be used for detection of BTLA by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BTLA |
|---|---|
| Alternative Names | BTLA Antibody : BTLA1 CD272 B- and T-lymphocyte attenuator B- and T-lymphocyte-associated protein |
| Molecular Weight(MW) | Predicted: 32 kDa Observed: 40kDa |
| Sequence Similarities | 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide |
| Tissue Specificity | BTLA antibody is human specific. At least two isoforms of BTLA are known to exist. |
Application
Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 μg/mL.
Application
Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 μg/mL.
Application
Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 μg/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | BTLA antibody can be used for detection of BTLA by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | BTLA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | BTLA Antibody is supplied in PBS containing 0.02% sodium azide. |
