Application
WB analysis of extracts from various cells using PSMC4 antibody.Application
IHC-P analysis of human breast cancer using PSMC4 antibody at a dilution of 1:100.Application
IHC-P analysis of human kidney using PSMC4 antibody at a dilution of 1:100.Application
IHC-P analysis of rat testis using PSMC4 antibody at a dilution of 1:100.Application
ICC/IF analysis of U2OS cells using PSMC4 antibody (red) and DAPI (blue).| Product Name | PSMC4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PSMC4The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms |
| Immunogen | Recombinant protein of human PSMC4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | S6 RPT3 TBP7 proteasome (prosome macropain) 26S subunit ATPase 4 MIP224 TBP-7 |
|---|---|
| Target | PSMC4 |
| Molecular Weight(MW) | 47 kDa (note) |
Application
WB analysis of extracts from various cells using PSMC4 antibody.
Application
IHC-P analysis of human breast cancer using PSMC4 antibody at a dilution of 1:100.
Application
IHC-P analysis of human kidney using PSMC4 antibody at a dilution of 1:100.
Application
IHC-P analysis of rat testis using PSMC4 antibody at a dilution of 1:100.
Application
ICC/IF analysis of U2OS cells using PSMC4 antibody (red) and DAPI (blue).| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
