Rabbit Polyclonal antibody to PSMG1 (proteasome (prosome, macropain) assembly chaperone 1)Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
Immunogen
Recombinant protein encompassing a sequence within the center region of human PSMG1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
C21LRP antibody DSCR2 antibody LRPC21 antibody PAC1 antibody PSMG1 antibody leucine rich protein C21-LRP antibody proteasome assembly chaperone 1 antibody PAC-1 antibody chromosome 21 leucine-rich protein antibody Down syndrome critical region gen
Molecular Weight(MW)
33 kDa (note) (4)
Application
Application
Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE diluted at 1:2000
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.