This gene encodes the peptide hormones calcitonin,
calcitonin gene-related peptide and katacalcin by tissue-specific
alternative RNA splicing of the gene transcripts and cleavage of
inactive precursor proteins. Calcitonin is involved in calcium
regulation and acts to regulate phosphorus metabolism. Calcitonin
gene-related peptide functions as a vasodilator while katacalcin is
a calcium-lowering peptide. Multiple transcript variants encoding
different isoforms have been found for this gene.1) Giroux, S., et al. Bone 47(5):975-981(2010)
Immunogen
This CALCA/CT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the C-terminal region of human CALCA/CT.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.