CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity .1) Pak JH, et al. Proc Natl Acad Sci U S A. 2000 Oct 10; 97 (21): 11232-11237 Hudmon A, et al. J Cell Biol. Author manuscript; available in PMC 2006 May 7Miller P, et al. PLoS Biol. 2005 Apr; 3 (4): e107Runyan JD, et al. Learn Mem. 2005 Mar; 12 (2): 103-110.
Immunogen
CaMKII (Phospho-Thr286) antibody was raised against a peptide sequence around phosphorylation site of threonine 286 (Q-E-T (p) -V-D) derived from Human CaMKII.