Application
Immunohistochemistry staining of CAND1 in kidney tissue using CAND1 Antibody.| Product Name | CAND1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1. |
| Immunogen | Amino acids 11-24 of Human CAND1/TIP120A (N-terminal) coupled to KLH. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIPWB |
| CAND1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CAND1 |
|---|---|
| Alternative Names | CAND1 KIAA0829 TBP interacting protein TBP-interacting protein 120A TIP120 p120 CAND1 TIP120A |
Application
Immunohistochemistry staining of CAND1 in kidney tissue using CAND1 Antibody.| Application Notes | CAND1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store CAND1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.01% sodium azide. |
