Western blot
Titration: 1 ug/mlPositive Control: mouse testis| Product Name | Rabbit anti-CAND1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp434M1414, FLJ10114, FLJ10929, FLJ38691, FLJ90441, KIAA0829, TIP120, TIP120A |
| Immunogen | The immunogen for anti-CAND1 antibody: synthetic peptide directed towards the middle region of human CAND1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CAND1 |
|---|---|
| Gene Synonyms | DKFZp434M1414 FLJ10114 FLJ10929 FLJ38691 FLJ90441 KIAA0829 TIP120 TIP120A |
| Gene Full Name | Cullin-associated and neddylation-dissociated 1 |
| Gene Summary | CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. |
| Alternative Names | DKFZp434M1414 FLJ10114 FLJ10929 FLJ38691 FLJ90441 KIAA0829 TIP120 TIP120A |
| Molecular Weight(MW) | 136kDa |
| Sequence | 1230 amino acids |
Western blot
Titration: 1 ug/mlPositive Control: mouse testis| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
