| Product Name |
CARMA1 Antibody |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
CARD11; Bimp3; Caspase Recruitment Domain-containing Protein 11; CARD-containing MAGUK Protein 1 |
| Product description |
CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR)-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK. |
| Immunogen |
N-terminal human CARMA1 (aa 1-221 containing the CARD domain). |