Application
Immunohistochemistry of Catheli-cidin in human spleen tissue with Cathelicidin antibody at 5 μg/mL.Application
Immunofluorescence of Cathelicidin in Human Spleen cells with Cathelicidin antibody at 20 μg/mL.Application
Immunohistochemistry of Cathelicidin in human spleen tissue with Cathelicidin antibody at 5 μg/ml.Application
Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 μg/mL.| Product Name | Cathelicidin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.1) Zaiou M and Gallo RL. Cathelicidins, essential gene-encoded mammalian antibiotics. J. Mol. Med. 2002; 80:549-61. |
| Immunogen | Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Cathelicidin. The immunogen is located within amino acids 50 - 100 of Cathelicidin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CAMP |
|---|---|
| Alternative Names | Cathelicidin Antibody: LL37 CAP18 CRAMP HSD26 CAP-18 FALL39 FALL-39 Cathelicidin antimicrobial peptide 18 kDa cationic antimicrobial protein |
| Molecular Weight(MW) | Predicted: 19 kDa Observed: 18 kDa |
| Sequence Similarities | 2) Cat. No. 10-901 - Human Spleen Tissue Slide |
Application
Immunohistochemistry of Catheli-cidin in human spleen tissue with Cathelicidin antibody at 5 μg/mL.
Application
Immunofluorescence of Cathelicidin in Human Spleen cells with Cathelicidin antibody at 20 μg/mL.
Application
Immunohistochemistry of Cathelicidin in human spleen tissue with Cathelicidin antibody at 5 μg/ml.
Application
Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 μg/mL.| Application Notes | Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Cathelicidin antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Cathelicidin Antibody is supplied in PBS containing 0.02% sodium azide. |
