Coiled-coil and C2 domain-containing protein 1A, Akt kinase-interacting protein 1, Five prime repressor element under dual repression-binding protein 1, FRE under dual repression-binding protein 1, Freud-1, Putative NF-kappa-B-activating protein 023N, CC2D
Product description
CC2D1A is a transcriptional repressor that binds
to a conserved 14-bp 5'-repressor element and regulates expression
of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal
cells. The DNA binding and transcriptional repressor activities of
the protein are inhibited by calcium. A mutation in this gene
results in nonsyndromic mental retardation-3.1) Zhao, M., et al. J. Biol. Chem. 285(32):24372-24380(2010)
Immunogen
This CC2D1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CC2D1A.
Coiled-coil and C2 domain-containing protein 1A Akt kinase-interacting protein 1 Five prime repressor element under dual repression-binding protein 1 FRE under dual repression-binding protein 1 Freud-1 Putative NF-kappa-B-activating protein 023N CC2D
Molecular Weight(MW)
104 kDa
Sequence Similarities
Predicted species reactivity based on immunogen sequence: Mouse
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.