Coiled-coil domain-containing protein 6, Papillary thyroid carcinoma-encoded protein, Protein H4, CCDC6, D10S170, TST1
Product description
This gene encodes a coiled-coil domain-containing protein.
The encoded protein is ubiquitously expressed and may function as a
tumor suppressor. A chromosomal rearrangement resulting in the
expression of a fusion gene containing a portion of this gene and
the intracellular kinase-encoding domain of the ret proto-oncogene
is the cause of thyroid papillary carcinoma.1) Leone, V., et al. Oncogene 29(30):4341-4351(2010)
Immunogen
This CCDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human CCDC6.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.