This gene is one of several CC cytokine genes clustered on
the p-arm of chromosome 9. Cytokines are a family of secreted
proteins involved in immunoregulatory and inflammatory processes.
The CC cytokines are proteins characterized by two adjacent
cysteines. The protein encoded by this gene is chemotactic for
skin-associated memory T lymphocytes. This cytokine may also play a
role in mediating homing of lymphocytes to cutaneous sites. It
specifically binds to chemokine receptor 10 (CCR10). Studies of a
similar murine protein indicate that these protein-receptor
interactions have a pivotal role in T cell-mediated skin
inflammation.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This CCL27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the C-terminal region of human CCL27.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.