Application
Western blot analysis of extracts from A549 cells (Lane 2), using CCR5 (Phospho-Ser349) Antibody. The lane on the left is treated with antigen-specific peptide.| Product Name | CCR5 (phospho Ser349) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C-C CKR-5, CKR5, CHEMR13, CMKBR5, CCR-5 |
| Product description | Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.1) Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875. |
| Immunogen | CCR5 (phospho Ser349) antibody was raised against a peptide sequence around phosphorylation site of Serine 349 (E-I-S (p)-V-G) derived from Human CCR5. |
| Modification | p-Ser349 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | C-C CKR-5 CKR5 CHEMR13 CMKBR5 CCR-5 |
|---|---|
| Molecular Weight(MW) | 40 kDa |
| Tissue Specificity | The antibody detects endogenous levels of CCR5 only when phosphorylated at serine 349. |
| Entrez Gene | 1234/727797 |
|---|---|
| Protein Accession | NP_000570.1 |
Application
Western blot analysis of extracts from A549 cells (Lane 2), using CCR5 (Phospho-Ser349) Antibody. The lane on the left is treated with antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
