Application
Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 μg/mL.Application
Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 μg/mL.Application
Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 μg/ml.| Product Name | CCR7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCR7 Antibody: BLR2, EBI1, CD197, CDw197, CMKBR7, EVI1, C-C chemokine receptor type 7, BLR2, C-C CKR-7 |
| Product description | The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1,2). The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor (3).1) Birkenbach M, Josefsen K, Yalamanchil R, et al. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. J. Virol. 1993; 67:2209-20. |
| Immunogen | CCR7 antibody was raised against a 15 amino acid peptide near the center of human CCR7. The immunogen is located within amino acids 180 - 230 of CCR7. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| CCR7 antibody can be used for detection of CCR7 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCR7 |
|---|---|
| Alternative Names | CCR7 Antibody: BLR2 EBI1 CD197 CDw197 CMKBR7 EVI1 C-C chemokine receptor type 7 BLR2 C-C CKR-7 |
| Molecular Weight(MW) | Predicted: 42 kDa Observed: 42 kDa |
| Sequence Similarities | 2) Cat. No. 10-901 - Human Spleen Tissue Slide |
| Tissue Specificity | CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins. |
Application
Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 μg/mL.
Application
Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 μg/mL.
Application
Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 μg/ml.| Positive Control | 1) Cat. No. 1306 - Human Spleen Tissue Lysate |
|---|---|
| Application Notes | CCR7 antibody can be used for detection of CCR7 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | CCR7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | CCR7 antibody is supplied in PBS containing 0.02% sodium azide. |
