Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.| Product Name | CCRL2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCRL2, CKRX, CRAM-A, CRAM-B, HCR, MGC116710, CRAM, ACKR5, CCRL2 |
| Product description | CCRL2 is a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. CCRL2 gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.1) Galligan, C.L., (2004) Arthritis Rheum. 50 (6), 1806-1814. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCRL2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| CCRL2 antibody can be used for detection of CCRL2 by ELISA at 1:1562500. CCRL2 antibody can be used for detection of CCRL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCRL2 |
|---|---|
| Alternative Names | CCRL2 CKRX CRAM-A CRAM-B HCR MGC116710 CRAM ACKR5 CCRL2 |
| Molecular Weight(MW) | 39 kDa |
Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.| Positive Control | 1) 721_B Cell Lysate |
|---|---|
| Application Notes | CCRL2 antibody can be used for detection of CCRL2 by ELISA at 1:1562500. CCRL2 antibody can be used for detection of CCRL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CCRL2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
