This gene encodes a chemokine receptor like protein, which
is predicted to be a seven transmembrane protein and most closely
related to CCR1. Chemokines and their receptors mediated signal
transduction are critical for the recruitment of effector immune
cells to the site of inflammation. This gene is expressed at high
levels in primary neutrophils and primary monocytes, and is further
upregulated on neutrophil activation and during monocyte to
macrophage differentiation. The function of this gene is unknown.
This gene is mapped to the region where the chemokine receptor gene
cluster is located.1) Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Immunogen
This CCRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human CCRL2.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.