| Product Name | CD137L Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 4-1BBL; TNFSF9 |
| Product description | The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response. |
| Immunogen | Recombinant human CD137L. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | FACSWB |
| Flow Cytometry: (1:1,000). Western Blot: (1:2,000). Optimal conditions must be determined individually for each application.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | TNFSF9 |
|---|---|
| Alternative Names | 4-1BBL TNFSF9 |
| Tissue Specificity | Recognizes human CD137L. Does not cross-react with mouse CD137L. |
| Application Notes | Flow Cytometry: (1:1,000). Western Blot: (1:2,000). Optimal conditions must be determined individually for each application.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
