| Product Name | PTPRA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to PTPRAProtein Tyrosine Phosphatase Alpha, a R4 receptor protein tyrosine phosphatase, is implicated in neuron formation, retinal development, cell adhesion, potassium channel regulation, nerve repair, insulin signaling, and cell cycle regulation. Protein Tyrosine Phosphatase Alpha activates the Src protein tyrosine kinase during mitosis, resulting in the transition from G2 to mitosis in the cell cycle. Protein Tyrosine Phosphatase Alpha is associated with carcinomas of breast, colon, oral squamous cell and prostate. A cytosolic form of Protein Tyrosine Phosphatase Alpha, p66 Protein Tyrosine Phosphatase Alpha, has recently been isolated. p66 Protein Tyrosine Phosphatase Alpha is produced by calpain-mediated proteolytic cleavage and its expression has been detected in nearly all cell types where Protein Tyrosine Phosphatase Alpha is expressed. |
| Immunogen | Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | HPTPalpha LRP RPTPA 5786 HLPR RPTPalpha PTPRL2 PTPRA 176884 R-PTP-alpha HPTPA PTPA HEPTP P18433 R PTP alpha |
|---|---|
| Target | PTPRA |
| Cellular Localization | Type I membrane protein |
| Application Notes | IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.01% Sodium Azide; Constituents: PBS. pH 7.4 |
