| Product Name | PTPRA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal to Human Protein Tyrosine Phosphatase Alpha ( PTPRA )PTP alpha, a R4 receptor protein tyrosine phosphatase, is implicated in neuron formation, retinal development, cell adhesion, potassium channel regulation, nerve repair, insulin signaling, and cell cycle regulation. PTP alpha activates the Src protein tyrosine kinase during mitosis, resulting in the transition from G2 to mitosis in the cell cycle. PTP alpha is associated with carcinomas of breast, colon, oral squamous cell and prostate. A cytosolic form of PTP alpha, p66 PTP alpha, has recently been isolated. p66 PTP alpha is produced by calpain-mediated proteolytic cleavage and its expression has been detected in nearly all cell types where PTP alpha is expressed. PTP alpha expression has been documented in human neoplastic breast, colon, prostate, and oral tissues, as well as in normal adipose, liver, skeletal muscle, and endothelial cells. ESTs have been isolated from a diverse set of normal and cancerous tissue libraries. |
| Immunogen | Synthetic peptide - KLH conjugated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | HPTPalpha LRP RPTPA 5786 HLPR RPTPalpha PTPRL2 PTPRA 176884 R-PTP-alpha HPTPA PTPA HEPTP P18433 R PTP alpha |
|---|---|
| Target | PTPRA |
| Application Notes | Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, pH 7.4 containing 0.01% sodium azide |
