| Product Name | PTPRB antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [122.2] to PTPRBPTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation. |
| Immunogen | Embryonic rat brain proteoglycans |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 122.2 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIPWB |
| Use between 1:1000-1:2500: |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | HPTP BETA HPTPB PTPB PTPRB R PTP BETA RPTPB |
|---|---|
| Target | PTPRB |
| Tissue Specificity | PTPRB |
| Application Notes | Use between 1:1000-1:2500: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | Antibody grown in protein free medium, then concentrated and dialysed against PBS |
